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Eurordis estimates

that as many as 5000 to 7000 distinct rare diseases exist, affecting for most of them a very small number of patients.

A disease or disorder

is defined as rare in Europe when it affects fewer than 1 in 2000 people.

Therapeutic options

for most of these diseases, for most of these patients and their families, are still to be invented, registered and marketed.

European Commission on Public Health defines rare diseases as

- life-threatening or chronically debilitating diseases which are of such low prevalence that special combined efforts are needed to address them -

About Us

Rare Insight Consulting has been created to support healthcare companies

Rare Insight Consulting

- will help new start-up biopharmaceutical companies establish their presence in Italy & Europe, as well as assisting well-established companies to bring solutions to people suffering from severe or orphan diseases. -

Rare Insight Consulting

is supported by:


20 years’

Orphan/Biotech Drugs market

Extensive knowledge’

of the commercial process in the
pharmaceutical environment

Solid experience’

in pharma companies start-up
and management

Leonardo Calzetti

Founding Partner

With more than 30 years in the pharmaceutical industry, Leonardo brings an extensive knowledge of the commercial process and a solid experience in pharma companies start-up and management.

Leonardo is founder of BluPhytal, a company which, through its Rare Insight Consulting division, supports healthcare companies to develop their presence in the Orphan Disease arena.
From 2016 to 2019 Leonardo has served as Head of Global Rare Diseases Franchise at Chiesi, managing the Strategic Marketing process and supporting Business Development activities.
From 2008 to 2015 Leonardo has created and developed the Italian affiliate of Swedish Orphan Biovitrum (SOBI), managing also Greece and Malta territories. In this role Leonardo has represented SOBI into Assobiotec (Italian Association for the Development of Biotechnologies) becoming member of the directive board.
Previously has spent 20 years in Chiesi Farmaceutici in positions with increasing responsibility in operational and strategic marketing, mainly in rare or severe diseases.

Our Expertise

Rare Insight Consulting
can provide, directly or through a network of selected partners,
a wide range of services
from strategic advice to practical solutions.

fields of expertise

Organizational set up and growth planning
Marketing and Communication
Commercial operations, Distribution and Tender
Market Access and Regulatory support
Medical services
Market research and Assessment

Go on, contact us!

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RARE INSIGHT CONSULTING is partner of a European network

We have worked with these companies

Case Studies

successful solutions for you!

Drug prelaunch activities


Take a look at case studies of our chosen company

Rare Insight has been and is an extremely valuable partner for Laboratoires CTRS.
They have effectively supported us in all phases (early access, price & reimbursement, launch strategy and tactics in the Italian market, KOL mapping, effective presentation of Orphacol advantages to treating physicians) allowing Orphacol to reach 100% of eligible patients.
Marco Liguori – Head of International Commercial Operations


There were some markets that were more difficult, in terms of previous relations we had with the Key Opinion Leaders, I have in mind for instance UK and ITALY and for some of these countries we have been able really to repair the relationships because of the local presence that was built.
Xavier Paoli – Pharnext Chief Commercial Officer
We are proud to see that our local presence, combined with strong experience and flexibility has been appreciated and made possible the development of the project in Italy, in coordination with our strategic partner BlueDil International.
Watch our partner testimony In the video below.


Rare Insight Consulting

Tel: +39 348 1518659
Mail: [email protected]

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